It's a grim end to a big round of footy at Adelaide Oval with Port hosting last-placed West Coast.
The resurgent Swans look to keep their slim finals hopes alive when they face St Kilda at Marvel on Sunday.
Sunday footy kicks off with a dead rubber between the Dees and Roos at the MCG.
Another pivotal top eight clash on Saturday sees Fremantle host Hawthorn at Optus.
The Tigers get a chance to end their seven-game losing run when they face Essendon at the MCG on Saturday night.
Another cracking contest on Saturday sees the Cats head to western Sydney to take on the Giants.
We should see fireworks at Marvel on Saturday when the Dogs play the Crows in a pivotal top eight battle.
The Suns host the Pies on Friday night in arguably the biggest match in the expansion club's history.
The weekend kicks off with the battling Blues facing off with the reigning premiers at Marvel Stadium.
The Crows will be hunting another big win when they host the Demons at the Adelaide Oval on Sunday.
An improved Swans outfit host Fremantle at the SCG to kick off Sunday footy.
The Hawks chase a fourth straight win when they meet the Saints at Marvel Stadium on Saturday night.
The Lions return from their bye to take on Port Adelaide at the Gabba on Saturday night.
The Tigers head down the highway to face Geelong in what looks like a total mismatch on paper.
The injury-plagued Bombers return from a break to take on the Suns, who are locked in a tight battle for a top eight berth.
The second Friday night match sees the bottom of the ladder host the Giants, who are chasing a third straight win.
The AFL's most storied rivalry adds a new chapter on Friday night when the battling Blues take on the top of the table Magpies.
The Roos celebrate 100 years in the AFL on Thursday night against the Western Bulldogs. It's unlikely to be a happy occasion.
Fremantle are big favourites to bring up a sixth-straight win when they take on St Kilda at Optus Stadium to close out Round 16.
The Crows will be hunting a percentage booster on Sunday when they take on the Tigers at the MCG.