In between two ripping derbies on Sunday sits this stinker between fourth-placed Hawthorn and 16th placed Richmond.
The first Sydney derby of 2025 sees the Giants comfortable favourites to beat the Swans at the SCG.
West Coast host Melbourne at Optus on Saturday night in one for the diehards only.
The Pies face the Cats in a blockbuster Saturday night match-up at the MCG.
The Crows host the Blues on Saturday afternoon with the visitors looking for a fourth straight win.
The Doggies head to Ballarat for the first time in 2025 to meet a resurgent Port Adelaide.
It's the Ross Lyon Cup at Marvel Stadium on Friday night with St Kilda hosting Fremantle.
Two of the biggest rivals of the 90s meet on Thursday night footy at Marvel with Essendon taking on North Melbourne.
The Hawks get a great opportunity for a percentage booster at Marvel Stadium when they face the winless Eagles.
Carlton will be looking for a third straight win when they meet Geelong at the MCG on Sunday afternoon.
The Suns will be looking to get back on the winners' list when they host Sydney on Sunday afternoon.
GWS head to Canberra for the first time this season to host the Western Bulldogs.
Port Adelaide will be looking to pile more pain on North Melbourne at the Adelaide Oval on Thursday night.
The Saints host the Lions at Marvel Stadium to kick off a Saturday triple-header.
The second ANZAC Day match sees the 3-3 Dockers hosting the 4-2 Crows at Optus Stadium.
Collingwood are big favourites for a sixth straight win when they face Essendon in the traditional ANZAC Day match.
The ANZAC Day Eve clash sees a battle of two bottom four sides, both coming off wins, in Melbourne and Richmond.
The Cats and the Hawks close out AFL Round 6 in the traditional Easter Monday clash at the MCG.
The Saints and the Bulldogs meet on Sunday night at Marvel Stadium in a battle of two evenly-matched sides.
The Swans host the Power on Sunday afternoon at the SCG with both sides sitting 2-3.