London hosts this AFC South clash with the Jags looking primed to use their travel experience to tighten their grip on the division.
Best Bet
AFC South rivals Jacksonville and Houston do battle in London and the location is all-important in this one.
Houston head for their first international game under DeMeco Ryans’ stewardship while the Jags have been regular visitors to London with Liam Coen’s team playing and winning there last week against the Eagles.
Coaches with a two-plus game edge in international coaching experience are 8-4 ATS in international games. Pre-bye favourites in international games are also 16-6 ATS.
Trevor Lawrence has covered four of five against CJ Stroud while teams with 12-plus days rest coming up are 21-11 ATS.
Jacksonville’s defence has been elite, conceding 20 or fewer in 11 straight games. They are one game off tying the best record for the last 30 years.
Everything lines up for the Jags in Week 6.
Same Game Multi
The under is 40-16-2 when a pre-bye team like the Jags plays a division rival while it is 4-1 in Stroud-Lawrence battles.
Woody Marks has assumed RB1 status with the Texans. He comes off a 15-carry, 62-yard game.
Bhayshul Tuten has been the most consistent running back in the NFL, running for between 65 yards and 73 yards in all five games this year.
Value Bet
Brenton Strange has featured heavily the last two weeks with Trevor Lawrence finding the tight end for 14 catches and 163 yards. He has had seven catches each of the last two weeks, both on eight targets apiece. Strange had his biggest game last season against the Texans in 2025 when he caught six balls for 61 yards. Everything is lining up for another big Lawrence-to-Strange game.
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