The traditional Easter Monday clash between Parramatta and the Wests Tigers is not as straight-up as many in the past with the Tigers coming off a very impressive win.
An injury-ravaged Cronulla host a Canberra team that has performed better than most expected but will be confident of collecting the two points.
The Warriors pulled off their first win of the season against the Raiders last week and will look to make it two straight when the Knights hit Auckland on Easter Sunday.
The second Queensland Derby of the weekend is receiving a lot less attention than the first though shapes as a critical game for both teams.
St George Illawarra disappointed last week when suffering a second straight flogging, this time on home turf, but getting a big start at home they need to be backed again.
The longest-standing Queensland derby has seen some of the great games played and this Friday's clash between the Broncos and Cowboys is expected to be no different.
The traditional Good Friday clash between South Sydney and Canterbury has long been the domain of the Rabbitohs but with the Bunnies on their knees, the Bulldogs are poised to strike.
Round 4 kicks off with an absolute belter from Allianz Stadium where the hot Chooks take on three-time premiers Penrith though the Panthers will be without star half Nathan Cleary.