If Benji Marshall has instilled any gumption in the Tigers side, they should be primed for a big bounceback performance against a Cronulla team riding high off two straight wins.
St George Illawarra were humiliated last week by the Dolphins and returning home there is no better spot to bet a team to bounce back.
Canterbury get a great chance to get off the mark at home against the Gold Coast and it is a chance the hapless Bulldogs look like they will take.
There is no more fierce rivalry in the NRL than that of the Roosters and Rabbitohs and with the Bunnies desperate and the Roosters focused, we are in for another brutal chapter.
New Zealand look to find their first win of the season in Christchurch on Friday night but it will not come easy against a Raiders team flying off back-to-back wins.
Round 3 opens with a rematch of last year's Grand Final but two key injuries to Brisbane make this one of the biggest mismatches of the week.