Round 3 closes with a must-win game for a winless Fremantle against their bitter crosstown rivals, West Coast.
The red hot Crows host the 1-1 Roos on Sunday afternoon in what should be a total shootout.
Rain could play havoc when the Cats travel north to play the Lions in a rescheduled game from Opening Round.
The Saints should go to 2-1 on the season when they host Richmond at Marvel on Saturday afternoon.
The Hawks host the Giants in Launceston on Saturday night in a blockbuster match-up between two 2025 flag contenders.
The Dees have dominated the Suns for years but that streak may come to an end on Saturday at the MCG.
The Blues are still in search of their first win of 2025 but it won't come easy against the Bulldogs on Friday night.
Bombers fans will be hoping for a strong response when their side host Port Adelaide at Marvel Stadium on Thursday night.