We have a shootout on our hands when NFC East also-rans Dallas and the New York Giants meet to round out the 2025 season.
It is the end of the line for AFC North rivals Cleveland and Cincinnati - and quite probably Browns coach Kevin Stefanski.
The Packers are set to start their third-string QB against the Vikings but look a great bet getting a big number.
The Bears are playoff bound while there will be no postseason action for Detroit after three straight losses leading into this game.
The Chargers are resting quarterback Justin Herbert and other key starters while the Broncos will be looking to lock up the top seed in the AFC.
The Buffalo Bills playoff incentives are limited but they will be keen to win what will almost certainly be their final ever game at Highmark Stadium.
The Buffalo Bills playoff incentives are limited but they will be keen to win what will almost certainly be their final ever game at Highmark Stadium.
Both the Saints and the Falcons are well out of the playoff race and despite Raheem Morris trying to save his job the hot Saints are the play.
The Jaguars have their playoff fate in their hands with a division win theirs if they can roll the lowly Titans at home as a near double-digit favourite.
The NFC West and the No.1 seed in the NFC will be decided when rivals Seattle and San Francisco meet at Levis in a regular season matchup for the ages.