Both teams are in the thick of the playoff race with just four weeks left in the regular season.
Best Bet
The 49ers showed last week that when they get key personnel back – most importantly quarterback Brock Purdy – they are still a force to be reckoned with in the NFC.
It’s been an all time Super Bowl hangover for San Francisco, who are 6-7 and desperately needing this win to make the playoffs.
They showed last week against Chicago that they are still a force to be reckoned with, as Brock Purdy played a near perfect game, completing 80% of his passes for 325 yards and two touchdowns.
The Niners also welcome Nick Bosa back for this game, as well as linebacker Dre Greenlaw, making his first appearance all season.
While the Rams did get the win over the 49ers at Levi’s Stadium last year, it was with both teams resting many of their key starters in what was essentially a dead rubber.
LA are coming off a big win against Buffalo last week but that 44-42 win demonstrated how vulnerable they can be defensively as well.
Like the Niners in this one.
Same Game Multi
The Rams have allowed 4.7 yards per carry this season and teams that run the ball well have exploited them. It’s next man up now for the 49ers at running back due to injuries, and that is now Isaac Guerdendo.
Cooper Kupp isn’t quite as explosive as he once was, but he has still managed to clear this mark in five of his last six games.
Value Bet
Star tight end Kittle is a huge price for first TD in this one given he has eight of the niners sixteen receiving scores on the season.
