San Francisco are still without quarterback Brock Purdy when they head to New York to play the Giants.
Featured Betting Sites
What are you prepared to lose today?
Set a deposit limit.
Best Bet
The 49ers have been smashed by injuries, leaving the Giants as the bet in this one.
The injury crisis in San Francisco really showed up last week against the Texans as they allowed 475 yards to an offence that has been poor this year.
Mac Jones has been serviceable replacing Brock Purdy, but the 49ers inability to run the ball – even with Christian McCaffrey at RB – means they may not be able to exploit the Giants biggest weakness, their run defence.
The Giants have won two of three at home with rookie Jaxson Dart at QB and they have been very solid defensively at home also, not allowing more than 22 points in three games.
The home side are the play here.
Same Game Multi
With Cam Skattebo out, Tyrone Tracy will be RB1 for the Giants and comes up against an offence that has allowed 50 or more receiving yards to RBs in four of their last five.
McCaffrey has been a dynamic pass catcher our the backfield this season and has cleared this mark in four of his last five.
Value Bet
With Cam Skattebo out former Bill Singletary should see more snaps at running back, and he is likely to be the primary ball carrier in goal line situations.
Follow Betseeker for free expert NFL betting tips for every game of the NFL season. Check out Betseeker’s top-rated betting sites and new betting sites to place your NFL bets!

















