NFL Tips – 49ers @ Bucs – Week 6 2025

Tampa and San Francisco have both started the season strongly and will be looking to consolidate their place at the top of the NFC.

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Best Bet

49ers +3.5
Line

The Bucs are well due for some regression so the 49ers with the points are the obvious play in this one.

All of Tampa’s wins this season have come by a field goal or less and they have a +4 turnover differential in games they have won.

Baker Mayfield is having a great season but he takes risks with the ball and sooner or later these will come back to bite.

Meanwhile for the 49ers Mac Jones is doing a more than adequate job standing in for Brock Purdy.

Baker is just 20-32-1 as a favourite so the 49ers are a very appealing play.


Same Game Multi

49ers +3.5, Jones Over 250.5 Passing Yards, McCaffrey Over 50.5 Receiving Yards
Same Game Multi

Mac Jones has cleared this number in all three games as starter and while the 49ers running game has struggled this year, McCaffrey has been brilliant as a pass catcher out of the backfield.


Value Bet

Mac Jones
Anytime TD

Jones mobility is somewhat underrated and he has rushed for three first downs this year. Happy to play him at a price to run one in.

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Frankie has spent more than a decade working in the Australian wagering industry and is widely regarded for his expertise in AFL, NRL and horse racing tips.